The Adar Lab
קבוצת אדר
The Hebrew University Faculty of Medicine
הפקולטה לרפואה של האוניברסיטה העברית
Publications
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Yaacov, A., Vardi, O., Blumenfeld, B., Greenberg, A., Massey, D.J., Koren, A., Adar, S., Simon, I. and Rosenberg, S., (2021). Cancer mutational processes vary in their association with replication timing and chromatin accessibility. bioRxiv.
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Golan Berman, H., Chauhan, P., Shalev, S., Hassanain, H., Parnas, A. and Adar, S., (2021). Genomic Characterization of Cisplatin Response Uncovers Priming of Cisplatin-Induced Genes in a Resistant Cell Line. International journal of molecular sciences, 22(11), p.5814.
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Heilbrun, E.E., Merav, M. and Adar, S., (2021). Exons and introns exhibit transcriptional strand asymmetry of dinucleotide distribution, damage formation and DNA repair. NAR genomics and bioinformatics, 3(1), p.lqab020.
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Heilbrun, EE., Merav, M., Parnas, A. and Adar, S. (2020). The Hardwired Transcriptional Response to DNA Damage. Current Opinion in Systems Biology.
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Van der Weegen, Y., Golan-Berman, H., Mevissen, T.E., Apelt, K., González-Prieto, R., Goedhart, J., Heilbrun, E.E., Vertegaal, A.C., van den Heuvel, D., Walter, J.C., Adar, S. and Luijsterburg M.S. (2020). The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II. Nature Communications, 11(1), 1-16.
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Milo-Cochavi, S., Adar, S. and Covo, S. (2019). Developmentally Regulated Oscillations in the Expression of UV Repair Genes in a Soilborne Plant Pathogen Dictate UV Repair Efficiency and Survival. Mbio, 10(6).
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Hu, J. Selby CP. Adar, S. Adebali, O. and Sancar A. (2017) Molecular mechanisms and genomic maps of DNA excision repair in E.coli and humans, J. Biol. Chem. J Biol Chem. 292(38):15588-15597.
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Hu, J. Adebali, O. Adar, S. and Sancar A. (2017) Dynamic maps of UV damage formation and repair for the human genome, Proc. Natl. Acad. Sci. U. S. A. 114(26):6758-6763.
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Li, W. Hu, J. Adebali, O. Adar, S. Yang, Y. Chiou, Y. and Sancar, A. (2017) Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene, Proc. Natl. Acad. Sci. U. S. A. 114(26), 6752-6757
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Hu, J. and Adar, S. (2017) The cartography of UV-induced DNA damage formation and DNA repair, The Journal of Photochemistry and Photobiology, 93(1), 199-206.
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Hu, J., Lieb, JD., Sancar, A., Adar, S. (2016), Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution. Proc. Natl. Acad. Sci. U. S. A. 113(41), 11507-11512.
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Adar, S. *, Hu, J. *, Lieb, JD. and Sancar, A. (2016), Genomewide kinetics of DNA excision repair in relation to chromatin state and mutagenesis. Proc. Natl. Acad. Sci. U. S. A. 113(6):E2124-E2133 *Equal contribution
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Hu, J. *, Adar, S. *, Selby, PY., Lieb, JD. and Sancar, A.(2015), Genome-Wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution. Genes and Development 29:948-960. *Equal contribution
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Annayev, Y., Adar, S., Chiou, YY., Lieb, JD., Sancar, A., Ye, R. (2014) Gene model 129 (gm129) encodes a novel transcriptional repressor that modulates circadian gene expression. J. Biol. Chem. 289(8):5013-24.
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ENCODE Project Consortium (2012), An integrated encyclopedia of DNA elements in the human genome. Nature 489(7414):57-74
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Adar, S., Izhar, L. Hendel, A., Geacintov, N. and Livneh, Z (2009). Repair of gaps opposite lesions by homologous recombination in mammalian cells. Nucleic Acid Research 37(17):5737-48.
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Shachar, S., Ziv, O., Avkin ,S., Adar, S., Wittschieben, J., Reibner, T. Chaney, S., Friedberg, EC., Wang, Z., Carell, T., Geacintov, N., (2009) Two-Polymerase Mechanisms Dictate Error-Free and Error-Prone Translesion DNA Synthesis in Mammals. EMBO J 28(4): 383-393.
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Adar, S. and Livneh, Z (2006). Translesion DNA synthesis across non-DNA segments in cultured human cells. DNA Repair 5(4):479-90.
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Avkin, S., Adar, S., Blander, G. and Livneh, Z. (2001). Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase. Proc. Natl. Acad. Sci. U. S. A. 99(6): 3764-9.